Tissues / Immuno - labeling
1Neuro filament labeling of spinal cord
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122
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Neurofilament is a protein present in the axons of the spinal cord. Multiple Sclerosis, a disease which degenerates this tissue, reduces the presence of the Nuerofilament. A recovery from the illness increases the presence of Neurofilament. By gold-labeling this protein and semi-quantifying the gold labels it is possible to assess the progression/regression of the illness. This sample of a spinal cord was labeled with 2nm gold particles and silver-enhanced.

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2Insulin gold immunolabeling in Pancreas
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123
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Gold-labeling of Insulin in pancreatic islets of Psammomys Obesus.
Left: Gold beads are present in the endocrine region (islet of Langerhans), and absent in the exocrine region, demonstrating the corresponding presence/lack of presence of Insulin in these regions.
Right: At higher magnification single gold beads are observed revealing insulin-containing secretory granules.

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